Structure of saframycin D, a new dimeric isoquinolinequinone antibiotic.
نویسندگان
چکیده
منابع مشابه
Saframycin Mx1, a new natural saframycin isolated from a myxobacterium.
A new natural saframycin was discovered in the culture broth of the myxobacterium, Myxococcus xanthus strain Mx x48. The fermentation and isolation of the antibiotic are described. The name, saframycin Mx1, is proposed. The compound appears to interact with cellular DNA.
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The biosynthesis of saframycin A, a heterocyclic quinone antitumor antibiotic isolated from Streptomyces lavendulae 314, was studied by feeding experiments with 14C and 13C precursors. Highly increased production of saframycin A and prolongation of the maximum production period of saframycin A were attained by constant pH control of the culture and by addition of chloramphenicol to the culture....
متن کاملStructure determination of pyracrimycin A, a new antibiotic substance.
mycin A on the basis of the chemical and physical properties and confirmed by the synthesis of the tetrahydro derivative III. Pyracrimycin A is a white crystalline substance, m. p. 215-216°G. The elemental analysis accounts for G7H10N2O(M. W. 138.17) confirmed by the M+ peak in the mass spectrum (Fig. 1). The IR spectrum (Fig. 2) is consistent with the presence of a primary amide group, as indi...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1987
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.35.440